Resources

Prof Simon Newstead Lab

Research in our group focuses on understanding how nutrient transporters function at a molecular level. In humans, many of the membrane proteins involved in absorbing nutrients from our diet are also responsible for drug transport and distribution into specific organs, including the central nervous system, liver, kidneys and GI tract. Nutrient transporters therefore have a profound impact on the pharmacokinetic properties of many administered drugs with clear medical advantages in understanding their structure, biochemistry and regulation.

Prof Gavin Thomas Lab

The primary overarching interest of the lab is the discovery and characterisation of transporters in bacteria. For over a decade our main experimental system has been a family of transporters called the TRAP transporters, which stand for tripartite ATP-independent periplasmic transporters. These transporters are found all over the bacteria world and have important functions in many environments, primarily as organic acid transporters of high affinity.

The molecular basis of thioalcohol production in human body odour

Michelle Rudden, Reyme Herman, Matthew Rose, Daniel Bawdon, Diana S. Cox, Eleanor Dodson, Matthew T. G. Holden, Anthony J. Wilkinson, A. Gordon James & Gavin H. Thomas

Structural basis of malodour precursor transport in the human axilla

Gurdeep S Minhas, Daniel Bawdon, Reyme Herman, Michelle Rudden, Andrew P Stone, A Gordon James, Gavin H Thomas & Simon Newstead.

Identification of axillary Staphylococcus sp. involved in the production of the malodorous thioalcohol 3-methyl-3-sufanylhexan-1-ol

Daniel Bawdon, Diana S. Cox, David Ashford, A. Gordon James, Gavin H. Thomas

Why are humans so smelly?

Find out about the bacteria that lurk in your armpit and how they cause body odour

Armpit Microbiome

Did you know that trillions of micro-organisms live on your skin and the highest number are in your armpit? Discover why bacteria love to live in your pits.

Bacterial Solute Transporters

Bacteria need to eat too and they take up molecules from their environment for food, learn more about how they do this here.

Nature Outline Article on the Skin Microbiome

The skin supports a diverse community of microorganisms that train and support the immune system, and fend off pathogenic threats.

Image Credit : Andrew Khosravani

What causes body odor? - Mel Rosenberg

Most of us don’t need more than one whiff to identify that generally unpleasant, characteristic smell we call body odor. But it’s a surprisingly complex phenomenon, influenced by our genetic makeup, age, diet, and hygiene. So what is this odor, exactly? Where does it come from? And can we do anything about it? Mel Rosenberg dives into the stinky science of body odor.